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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

P2RY1 Antibody

CATALOG NUMBER: 57-841

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat
Immunogen:
This P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the Central region of human P2RY1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
P2RY1
Additional Names:
P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1
Protein Accession Number:
P47900
Protein Gi Number:
1352692
Ncbi Gene Id Number:
5028
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the family ofG-protein coupled receptors. This family has several receptorsubtypes with different pharmacological selectivity, which overlapsin some cases, for various adenosine and uridine nucleotides. Thisreceptor functions as a receptor for extracellular ATP and ADP. Inplatelets binding to ADP leads to mobilization of intracellularcalcium ions via activation of phospholipase C, a change inplatelet shape, and probably to platelet aggregation. [provided byRefSeq].
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Maloney, S.F., et al. Integr Biol (Camb) 2(4):183-192(2010)
Background Reference 3:
Nisar, S., et al. Traffic 11(4):508-519(2010)
Background Reference 4:
Kumar, T.S., et al. J. Med. Chem. 53(6):2562-2576(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-841

List Size:
400 ul

List Price:

$495.00

Datasheet
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