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Western blot analysis of lysed extracts from 293 cells using p70 S6 Kinase (Ab-421).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p70 S6 Kinase (Ab-421).
Western blot analysis of lysed extracts from 293 cells using p70 S6 Kinase (Ab-421).

p70 S6 Kinase (Ab 421) Antibody

CATALOG NUMBER: 79-382

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
p70 S6 Kinase (Ab-421) antibody was raised against a peptide sequence around aa.419~423 (P-R-T-P-V) derived from Human p70 S6 Kinase.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
This antibody detects endogenous level of total p70 S6 Kinase protein.
Predicted Molecular Weight:
70 85 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
RPS6KB1
Additional Names:
S6K, PS6K, S6K1, STK14A, p70-S6K, p70S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha, MAPTL, MTBT1, TAU, KS6B1, P70-S6K, RPS6KB1, S6K
Protein Accession Number:
NP_003152.1
Protein Gi Number:
4506737
Ncbi Gene Id Number:
6198
Background:
Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens. Promotes protein synthesis by phosphorylating PDCD4 at 'Ser-67' and targeting it for degradation.
Background Reference 1:
Xiao-Feng, et al. (2003) Le1 30 Volume 22: 484-497An WL, et al. (2003) Am J Pathol. 163 (2): 591-607. Le XF, et al. (2003) Oncogene. 22 (4): 484-97

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-382

List Size:
0.1 mg

List Price:

$320.00

Out of stock

Datasheet
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