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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

PACRG Antibody

CATALOG NUMBER: 59-356

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PACRG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human PACRG.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
33 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PACRG
Additional Names:
Parkin coregulated gene protein, Molecular chaperone/chaperonin-binding protein, PARK2 coregulated gene protein, PACRG, GLUP
Protein Accession Number:
Q96M98
Protein Gi Number:
77416872
Ncbi Gene Id Number:
135138
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is conserved acrossmetazoans. In vertebrates, this gene is linked in a head-to-headarrangement with the adjacent parkin gene, which is associated withautosomal recessive juvenile Parkinson's disease. These genes areco-regulated in various tissues and they share a bi-directionalpromoter. Both genes are associated with susceptibility to leprosy.The parkin co-regulated gene protein forms a large molecularcomplex with chaperones, including heat shock proteins 70 and 90,and chaperonin components. This protein is also a component of Lewybodies in Parkinson's disease patients, and it suppresses unfoldedPael receptor-induced neuronal cell death. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Wilson, G.R., et al. Fertil. Steril. 93(7):2262-2268(2010)
Background Reference 3:
Dagda, R.K., et al. J. Bioenerg. Biomembr. 41(6):473-479(2009)
Background Reference 4:
Velez, D.R., et al. Int. J. Tuberc. Lung Dis. 13(9):1068-1076(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-356

List Size:
400 ul

List Price:

$495.00

Datasheet
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