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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

PADI2 Antibody

CATALOG NUMBER: 57-682

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PADI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human PADI2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
76 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PADI2
Additional Names:
Protein-arginine deiminase type-2, PAD-H19, Peptidylarginine deiminase II, Protein-arginine deiminase type II, PADI2, KIAA0994, PDI2
Protein Accession Number:
Q9Y2J8
Protein Gi Number:
7531171
Ncbi Gene Id Number:
11240
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the peptidyl argininedeiminase family of enzymes, which catalyze the post-translationaldeimination of proteins by converting arginine residues intocitrullines in the presence of calcium ions. The family membershave distinct substrate specificities and tissue-specificexpression patterns. The type II enzyme is the most widelyexpressed family member. Known substrates for this enzyme includemyelin basic protein in the central nervous system and vimentin inskeletal muscle and macrophages. This enzyme is thought to play arole in the onset and progression of neurodegenerative humandisorders, including Alzheimer disease and multiple sclerosis, andit has also been implicated in glaucoma pathogenesis. This geneexists in a cluster with four other paralogous genes. [provided byRefSeq].
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Jang, B., et al. Acta Neuropathol. 119(2):199-210(2010)
Background Reference 3:
Cafaro, T.A., et al. Mol. Vis. 16, 1654-1658 (2010) :
Background Reference 4:
Hojo-Nakashima, I., et al. J. Biochem. 146(4):471-479(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-682

List Size:
400 ul

List Price:

$495.00

Datasheet
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