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Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody. The lane on the left is treated with antigen-specific peptide.
Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody. The lane on the left is treated with antigen-specific peptide.

PAK5/6 (phospho Ser602/Ser560) Antibody

CATALOG NUMBER: 79-921

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
PAK5/6 (phospho Ser602/Ser560) antibody was raised against a peptide sequence around phosphorylation site of Serine 602/560 (R-K-S (p)-L-V) derived from Human PAK5/6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560.
Predicted Molecular Weight:
75 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
PAK5, PAK6
Additional Names:
PAK5, PAK 6, kinase PAK6
Protein Accession Number:
NP_065074.1
Protein Gi Number:
24308191
Ncbi Gene Id Number:
57144;56924
Background:
This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development.
Background Reference 1:
Yang F., J. Biol. Chem. 276:15345-15353(2001).
Background Reference 2:
Wagner T., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases.
Background Reference 3:
Sjoeblom T., Science 314:268-274(2006).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-921

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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