PANX2 Antibody

CATALOG NUMBER: 60-373

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PANX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the C-terminal region of human PANX2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
74 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PANX2
Additional Names:
Pannexin-2, PANX2
Protein Accession Number:
Q96RD6
Protein Gi Number:
296439257
Ncbi Gene Id Number:
56666
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene belongs to the innexinfamily. Innexin family members are the structural components of gapjunctions. This protein and pannexin 1 are abundantly expressed incentral nervous system (CNS) and are coexpressed in variousneuronal populations. Studies in Xenopus oocytes suggest that thisprotein alone and in combination with pannexin 1 may form celltype-specific gap junctions with distinct properties. Multipletranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Ambrosi, C., et al. J. Biol. Chem. 285(32):24420-24431(2010)
Background Reference 2:
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Background Reference 3:
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Background Reference 4:
Lai, C.P., et al. Oncogene 28(49):4402-4408(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-373

List Size:
400 ul

List Price:

$495.00

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