PARP2 Antibody

CATALOG NUMBER: 27-940

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
PARP2 antibody can be used for detection of PARP2 by ELISA at 1:62500. PARP2 antibody can be used for detection of PARP2 by western blot at 1.6 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1207 - Raji Cell Lysate
Predicted Molecular Weight:
61 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store PARP2 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
PARP2
Additional Names:
PARP2, ARTD2, ADPRT2, PARP-2, ADPRTL2, ADPRTL3, pADPRT-2
Protein Accession Number:
NP_005475
Protein Gi Number:
110825961
Ncbi Gene Id Number:
10038
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PARP2 contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.
Background Reference 1:
Malanga, M. et al., (2004) J. Biol. Chem. 279 (7), 5244-5248.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-940

List Size:
100 ul

List Price:

$519.00

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