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Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

PARP2 Antibody

CATALOG NUMBER: 56-362

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PARP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-336 amino acids from the C-terminal region of human PARP2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
63 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
Parp2
Additional Names:
Poly [ADP-ribose] polymerase 2, PARP-2, mPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2, Parp2, Adprt2, Adprtl2, Aspartl2
Protein Accession Number:
O88554
Ncbi Gene Id Number:
11546
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Parp2 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Background Reference 1:
Brunyanszki, A., et al. J. Invest. Dermatol. 130(11):2629-2637(2010)
Background Reference 2:
Toller, I.M., et al. Cancer Res. 70(14):5912-5922(2010)
Background Reference 3:
Nicolas, L., et al. Oncogene 29(19):2877-2883(2010)
Background Reference 4:
Li, X., et al. J. Neurochem. 113(4):1012-1022(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-362

List Size:
400 ul

List Price:

$495.00

Datasheet
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