PAX2 Antibody

CATALOG NUMBER: 58-879

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PAX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human PAX2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PAX2
Additional Names:
Paired box protein Pax-2, PAX2
Protein Accession Number:
Q02962
Protein Gi Number:
223590261
Ncbi Gene Id Number:
5076
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PAX2 encodes paired box gene 2, one of many humanhomologues of the Drosophila melanogaster gene prd. The centralfeature of this transcription factor gene family is the conservedDNA-binding paired box domain. PAX2 is believed to be a target oftranscriptional supression by the tumor supressor gene WT1.Mutations within PAX2 have been shown to result in optic nervecolobomas and renal hypoplasia. Alternative splicing of this generesults in multiple transcript variants.
Background Reference 1:
Monte, N.M., et al. Cancer Res. 70(15):6225-6232(2010)
Background Reference 2:
Ozcan, A., et al. Arch. Pathol. Lab. Med. 134(8):1121-1129(2010)
Background Reference 3:
Quick, C.M., et al. Hum. Pathol. 41(8):1145-1149(2010)
Background Reference 4:
Martinovic-Bouriel, J., et al. Am. J. Med. Genet.152A (4), 830-835 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-879

List Size:
400 ul

List Price:

$495.00

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