PAX7 Antibody

CATALOG NUMBER: 55-213

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human PAX7.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
57 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PAX7
Additional Names:
Paired box protein Pax-7, HuP1, PAX7, HUP1
Protein Accession Number:
P23759
Protein Gi Number:
8247951
Ncbi Gene Id Number:
5081
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PAX7 is a member of the paired box (PAX) family oftranscription factors. Members of this gene family typicallycontain a paired box domain, an octapeptide, and a paired-typehomeodomain. These genes play critical roles during fetaldevelopment and cancer growth. The specific function of the pairedbox 7 gene is unknown but speculated to involve tumor suppressionsince fusion of this gene with a forkhead domain family member hasbeen associated with alveolar rhabdomyosarcoma. Three transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 2:
Williamson, D., et al. J. Clin. Oncol. 28(13):2151-2158(2010)
Background Reference 3:
Xynos, A., et al. Stem Cells 28(5):965-973(2010)
Background Reference 4:
Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-213

List Size:
400 ul

List Price:

$495.00

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