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Antibody used in IHC on Human Liver.
Antibody used in WB on Human HepG2 at 0.5-1.0 ug/ml.
Antibody used in IHC on Human Liver.

PC4 Antibody

CATALOG NUMBER: 31-238

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat, Zebrafish
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PC4.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
PC4 antibody can be used for detection of PC4 by ELISA at 1:7812500. PC4 antibody can be used for detection of PC4 by western blot at 0.5-1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
14 kDa
Purification:
Antibody is supplied as total IgG.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store PC4 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
SUB1
Additional Names:
PC4, P15, PC4, p14
Protein Accession Number:
NP_006704
Protein Gi Number:
217330646
Ncbi Gene Id Number:
10923
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
Background Reference 1:
Banerjee, S., et al., (2004) Cell.Biol.24(5), 2052-2062.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

31-238

List Size:
100 ul

List Price:

$473.00

Datasheet
Shipping Info

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