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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

PDC Antibody

CATALOG NUMBER: 56-429

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human PDC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDC
Additional Names:
Phosducin, PHD, 33 kDa phototransducing protein, Protein MEKA, PDC
Protein Accession Number:
P20941
Protein Gi Number:
130134
Ncbi Gene Id Number:
5132
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a phosphoprotein, which is located inthe outer and inner segments of the rod cells in the retina. Thisprotein may participate in the regulation of visualphototransduction or in the integration of photoreceptormetabolism. It modulates the phototransduction cascade byinteracting with the beta and gamma subunits of the retinalG-protein transducin. This gene is a potential candidate gene forretinitis pigmentosa and Usher syndrome type II. Alternativelyspliced transcript variants encoding different isoforms have beenidentified.
Background Reference 1:
Beetz, N., et al. J. Clin. Invest. 119(12):3597-3612(2009)
Background Reference 2:
Klenk, C., et al. J. Biol. Chem. 281(13):8357-8364(2006)
Background Reference 3:
Nishiguchi, K.M., et al. Mol. Vis. 10, 62-64 (2004) :
Background Reference 4:
Margulis, A., et al. Mol. Vis. 8, 477-482 (2002) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-429

List Size:
400 ul

List Price:

$495.00

Datasheet
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