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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

PDCD10 Antibody

CATALOG NUMBER: 59-576

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Chicken, Mouse, Rat, Xenopus
Immunogen:
This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
25 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDCD10
Additional Names:
Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
Protein Accession Number:
Q9BUL8
Protein Gi Number:
74733232
Ncbi Gene Id Number:
11235
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes an evolutionarily conserved proteinassociated with cell apoptosis. The protein interacts with theserine/threonine protein kinase MST4 to modulate the extracellularsignal-regulated kinase (ERK) pathway. It also interacts with andis phosphoryated by serine/threonine kinase 25, and is thought tofunction in a signaling pathway essential for vascular developent.Mutations in this gene are one cause of cerebral cavernousmalformations, which are vascular malformations that cause seizuresand cerebral hemorrhages. Multiple alternatively spliced variants,encoding the same protein, have been identified. [provided byRefSeq].
Background Reference 1:
Lauenborg, B., et al. APMIS 118(10):719-728(2010)
Background Reference 2:
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Background Reference 3:
Ding, J., et al. Biochem. Biophys. Res. Commun. 399(4):587-592(2010)
Background Reference 4:
Zheng, X., et al. J. Clin. Invest. 120(8):2795-2804(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-576

List Size:
400 ul

List Price:

$495.00

Datasheet
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