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Western blot analysis in A549 cell line lysates (35ug/lane).
Western blot analysis in A549 cell line lysates (35ug/lane).

PDCD6 Antibody

CATALOG NUMBER: 60-784

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PDCD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of human PDCD6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
22 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDCD6
Additional Names:
Programmed cell death protein 6, Apoptosis-linked gene 2 protein, Probable calcium-binding protein ALG-2, PDCD6, ALG2
Protein Accession Number:
O75340
Ncbi Gene Id Number:
10016
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a calcium-binding protein belonging tothe penta-EF-hand protein family. Calcium binding is important forhomodimerization and for conformational changes required forbinding to other protein partners. This gene product participatesin T cell receptor-, Fas-, and glucocorticoid-induced programmedcell death. In mice deficient for this gene product, however,apoptosis was not blocked suggesting this gene product isfunctionally redundant.
Background Reference 1:
Vergarajauregui, S., et al. J. Biol. Chem. 284(52):36357-36366(2009)
Background Reference 2:
Okumura, M., et al. Biochem. Biophys. Res. Commun. 386(1):237-241(2009)
Background Reference 3:
Suzuki, H., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 11), 974-977 (2008) :
Background Reference 4:
Yamada, Y., et al. Cancer Sci. 99(11):2193-2199(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-784

List Size:
400 ul

List Price:

$495.00

Datasheet
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