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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

PDCD6IP Antibody

CATALOG NUMBER: 60-809

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PDCD6IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-570 amino acids from the Central region of human PDCD6IP.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
96 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDCD6IP
Additional Names:
Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375
Protein Accession Number:
Q8WUM4
Protein Gi Number:
31076831
Ncbi Gene Id Number:
10015
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein thought to participate inprogrammed cell death. Studies using mouse cells have shown thatoverexpression of this protein can block apoptosis. In addition,the product of this gene binds to the product of the PDCD6 gene, aprotein required for apoptosis, in a calcium-dependent manner. Thisgene product also binds to endophilins, proteins that regulatemembrane shape during endocytosis. Overexpression of this geneproduct and endophilins results in cytoplasmic vacuolization, whichmay be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Shi, X., et al. Biochem. J. 431(1):93-102(2010)
Background Reference 2:
Irie, T., et al. Virology 405(2):334-341(2010)
Background Reference 3:
Sette, P., et al. J. Virol. 84(16):8181-8192(2010)
Background Reference 4:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-809

List Size:
400 ul

List Price:

$495.00

Datasheet
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