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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

PDE4A Antibody

CATALOG NUMBER: 59-005

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This PDE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human PDE4A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
98 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDE4A
Additional Names:
cAMP-specific 3',5'-cyclic phosphodiesterase 4A, DPDE2, PDE46, PDE4A, DPDE2
Protein Accession Number:
P27815
Protein Gi Number:
116242706
Ncbi Gene Id Number:
5141
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cyclic nucleotides are important second messengers thatregulate and mediate a number of cellular responses toextracellular signals, such as hormones, light, andneurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs)regulate the cellular concentrations of cyclic nucleotides andthereby play a role in signal transduction. PDE4A is a class IVcAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed8009369]).
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Selige, J., et al. J. Cell. Physiol. 223(2):317-326(2010)
Background Reference 3:
Bjorgo, E., et al. Mol. Cell. Biol. 30(7):1660-1672(2010)
Background Reference 4:
Singh, D., et al. Respir. Res. 11, 26 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-005

List Size:
400 ul

List Price:

$495.00

Datasheet
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