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Western blot analysis in mouse heart tissue lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

PDE8B Antibody

CATALOG NUMBER: 60-835

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
99 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDE8B
Additional Names:
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B, HsPDE8B, Cell proliferation-inducing gene 22 protein, PDE8B
Protein Accession Number:
O95263
Ncbi Gene Id Number:
8622
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a cyclic nucleotidephosphodiesterase (PDE) that catalyzes the hydrolysis of the secondmessenger cAMP. The encoded protein, which does not hydrolyze cGMP,is resistant to several PDE inhibitors. Defects in this gene are acause of autosomal dominant striatal degeneration (ADSD). Severaltranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Horvath, A., et al. Thyroid 20(4):363-367(2010)
Background Reference 2:
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 3:
Appenzeller, S., et al. Am. J. Hum. Genet. 86(1):83-87(2010)
Background Reference 4:
Shields, B.M., et al. J. Clin. Endocrinol. Metab. 94(11):4608-4612(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-835

List Size:
400 ul

List Price:

$495.00

Datasheet
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