PDGFRL Antibody

CATALOG NUMBER: 59-183

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Immunogen:
This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PDGFRL
Additional Names:
Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS
Protein Accession Number:
Q15198
Protein Gi Number:
74762141
Ncbi Gene Id Number:
5157
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein with significant sequencesimilarity to the ligand binding domain of platelet-derived growthfactor receptor beta. Mutations in this gene, or deletion of achromosomal segment containing this gene, are associated withsporadic hepatocellular carcinomas, colorectal cancers, andnon-small cell lung cancers. This suggests this gene product mayfunction as a tumor suppressor.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010)
Background Reference 3:
Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :
Background Reference 4:
Xu, M., et al. BMC GenomicsSUPPL 1, S12 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-183

List Size:
400 ul

List Price:

$495.00

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