PF4 Antibody

CATALOG NUMBER: 61-201

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PF4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from human PF4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
11 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PF4
Additional Names:
Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Platelet factor 4, short form, PF4, CXCL4, SCYB4
Protein Accession Number:
P02776
Protein Gi Number:
130304
Ncbi Gene Id Number:
5196
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Background Reference 1:
Poncz M.,et al.Blood 69:219-223(1987).
Background Reference 2:
Eisman R.,et al.Blood 76:336-344(1990).
Background Reference 3:
Zhang C.,et al.Blood 98:610-617(2001).
Background Reference 4:
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

61-201

List Size:
200 ul

List Price:

$495.00

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