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PGAM5 (CT) Peptide

CATALOG NUMBER: 9517P

Tested Applications:
Blocking
Specifications
Peptide Aa Location:
14 amino acids near the carboxy terminus of PGAM5 (CT).
Species:
Human
Tested Applications:
Blocking
Application Note:
PGAM5 (CT) Peptideis used for blocking the activity of thePGAM5 (CT) Antibody
Physical State:
Liquid
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and ≤0.09% sodium azide
Concentration:
200 ug/mL
Storage Conditions:
Store PGAM5 (CT) Peptide at -20°C, stable for one year.
Ncbi Official Symbol:
PGAM5
Additional Names:
Serine/threonine-protein phosphatase PGAM5 mitochondrial, Bcl-XL-binding protein v68, Phosphoglycerate mutase family member 5
Protein Accession Number:
Q96HS1
Protein Gi Number:
150417955
Ncbi Gene Id Number:
192111
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PGAM5 Antibody: PGAM5 is a central mediator for programmed necrosis induced by TNF and may be a regulator of mitochondrial dynamics. It displays phosphatase activity for serine/threonine residues, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and is a substrate for a KEAP1-dependent ubiquitin ligase complex. It is also contributes to the repression of NFE2L2-dependent gene expression
Background Reference 1:
Lo S. et al. Exp. Cell Res. 2018; 314(8): 1789-1803
Background Reference 2:
Takeda et al. PNAS 2009; 106(30): 12301-12305
Background Reference 3:
Want et al. Cell 2012; 148(1-2); 228-243

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

9517P

List Size:
0.05 mg

List Price:

$119.00

Datasheet
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