PHEX Antibody

CATALOG NUMBER: 58-750

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PHEX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the C-terminal region of human PHEX.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
86 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PHEX
Additional Names:
Phosphate-regulating neutral endopeptidase, 3424-, Metalloendopeptidase homolog PEX, Vitamin D-resistant hypophosphatemic rickets protein, X-linked hypophosphatemia protein, HYP, PHEX, PEX
Protein Accession Number:
P78562
Protein Gi Number:
2499917
Ncbi Gene Id Number:
5251
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a transmembraneendopeptidase that belongs to the type II integral membranezinc-dependent endopeptidase family. The protein is thought to beinvolved in bone and dentin mineralization and renal phosphatereabsorption. Mutations in this gene cause X-linkedhypophosphatemic rickets.
Background Reference 1:
Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010)
Background Reference 2:
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Background Reference 3:
Clausmeyer, S., et al. Calcif. Tissue Int. 85(3):211-220(2009)
Background Reference 4:
Gaucher, C., et al. Hum. Genet. 125(4):401-411(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-750

List Size:
400 ul

List Price:

$495.00

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