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Western blot analysis of PI3KCG Antibody in K562 cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
Western blot analysis of PI3KCG Antibody in K562 cell line lysates (35ug/lane)

PI3KCG Antibody

CATALOG NUMBER: 63-348

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Pig
Immunogen:
This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1074-1102 amino acids from the C-terminal region of human PI3KCG.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
126 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PIK3CG
Additional Names:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma, PtdIns-3-kinase subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, PtdIns-3-kinase subunit p110-gamma, p110gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, Serine/threonine protein kinase PIK3CG, p120-PI3K, PIK3CG
Protein Accession Number:
P48736
Protein Gi Number:
92090623
Ncbi Gene Id Number:
5294
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.
Background Reference 1:
Resendiz, J.C., et al., Mol. Pharmacol. 63(3):639-645 (2003).
Background Reference 2:
Francois, F., et al., J. Virol. 77(4):2539-2549 (2003).
Background Reference 3:
Chandrasekar, N., et al., Oncogene 22(3):392-400 (2003).
Background Reference 4:
Ishibashi, Y., et al., Cell. Microbiol. 4(12):825-833 (2002).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-348

List Size:
400 ul

List Price:

$495.00

Datasheet
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