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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

PIG3 Antibody

CATALOG NUMBER: 60-424

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PIG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-203 amino acids from the C-terminal region of human PIG3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
36 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TP53I3
Additional Names:
Quinone oxidoreductase PIG3, 1---, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein, TP53I3, PIG3
Protein Accession Number:
Q53FA7
Protein Gi Number:
76789665
Ncbi Gene Id Number:
9540
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is similar tooxidoreductases, which are enzymes involved in cellular responsesto oxidative stresses and irradiation. This gene is induced by thetumor suppressor p53 and is thought to be involved in p53-mediatedcell death. It contains a p53 consensus binding site in itspromoter region and a downstream pentanucleotide microsatellitesequence. P53 has been shown to transcriptionally activate thisgene by interacting with the downstream pentanucleotidemicrosatellite sequence. The microsatellite is polymorphic, with avarying number of pentanucleotide repeats directly correlated withthe extent of transcriptional activation by p53. It has beensuggested that the microsatellite polymorphism may be associatedwith differential susceptibility to cancer. At least two transcriptvariants encoding the same protein have been found for this gene.
Background Reference 1:
Kotsinas, A., et al. Oncogene 29 (37), 5220 (2010) :
Background Reference 2:
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Background Reference 3:
Lee, J.H., et al. Oncogene 29(10):1431-1450(2010)
Background Reference 4:
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-424

List Size:
400 ul

List Price:

$495.00

Datasheet
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