PIGT Antibody

CATALOG NUMBER: 58-317

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PIGT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of human PIGT.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
66 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PIGT
Additional Names:
GPI transamidase component PIG-T, Phosphatidylinositol-glycan biosynthesis class T protein, PIGT
Protein Accession Number:
Q969N2
Protein Gi Number:
44888284
Ncbi Gene Id Number:
51604
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that is involved inglycosylphosphatidylinositol (GPI)-anchor biosynthesis. TheGPI-anchor is a glycolipid found on many blood cells and serves toanchor proteins to the cell surface. This protein is an essentialcomponent of the multisubunit enzyme, GPI transamidase. GPItransamidase mediates GPI anchoring in the endoplasmic reticulum,by catalyzing the transfer of fully assembled GPI units toproteins. Several transcript variants encoding different isoformshave been found for this gene.
Background Reference 1:
Li, H.L., et al. FEBS Lett. 580(7):1723-1728(2006)
Background Reference 2:
Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)
Background Reference 3:
Ohishi, K., et al. J. Biol. Chem. 278(16):13959-13967(2003)
Background Reference 4:
Eisenhaber, B., et al. Bioessays 25(4):367-385(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-317

List Size:
400 ul

List Price:

$495.00

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