PIK3AP1 Antibody

CATALOG NUMBER: 56-700

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PIK3AP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human PIK3AP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
90 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PIK3AP1
Additional Names:
Phosphoinositide 3-kinase adapter protein 1, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, BCAP
Protein Accession Number:
Q6ZUJ8
Protein Gi Number:
205830907
Ncbi Gene Id Number:
118788
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).
Background Reference 1:
Koutros, S., et al. Cancer Res. 70(6):2389-2396(2010)
Background Reference 2:
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Background Reference 3:
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Background Reference 4:
Maruoka, M., et al. FEBS Lett. 579(14):2986-2990(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-700

List Size:
400 ul

List Price:

$495.00

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