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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

PIK3IP1 Antibody

CATALOG NUMBER: 57-275

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PIK3IP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the C-terminal region of human PIK3IP1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
28 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PIK3IP1
Additional Names:
Phosphoinositide-3-kinase-interacting protein 1, Kringle domain-containing protein HGFL, PIK3IP1, HGFL
Protein Accession Number:
Q96FE7
Protein Gi Number:
134034149
Ncbi Gene Id Number:
113791
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PIK3IP1 is a novel protein that shares homology with the p85 subunit of phosphatidylinositol-3-Kinases (PI3Ks). The PI3K is essential for cell proliferation and Survival.The PIK3IP down regulates the activity of the PI3K and induces apoptosis by associating with p85 and p110 to form a complex, using the p85-like domain. However, there is no evidence to suggest that the PIK3IP1 prevents association of p85 and p110 as they associate with very high affinity.
Background Reference 1:
Gao, P., et al. Beijing Da Xue Xue Bao 40(6):572-577(2008)
Background Reference 2:
He, X., et al. Cancer Res. 68(14):5591-5598(2008)
Background Reference 3:
Zhu, Z., et al. Biochem. Biophys. Res. Commun. 358(1):66-72(2007)
Background Reference 4:
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-275

List Size:
400 ul

List Price:

$495.00

Datasheet
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