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Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) Antibody. The lane on the right is treated with the antigen-specific peptide.

PKCD (phospho Tyr64) Antibody

CATALOG NUMBER: 79-973

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
PKCD (phospho Tyr64) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y (p)-E-G) derived from Human PKCD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of PKCD only when phosphorylated at tyrosine 64.
Predicted Molecular Weight:
78 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
PRKCD
Additional Names:
KPCD, PKC-delta, PRKCD, kinase PKC-delta, nPKC-delta
Protein Accession Number:
NP_006245.2
Protein Gi Number:
31377782
Ncbi Gene Id Number:
5580
Background:
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses.
Background Reference 1:
Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 283, 17731-9.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-973

List Size:
0.1 mg

List Price:

$355.00

Out of stock

Datasheet
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