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Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PLC-γ2 (Ab-1217).
Immunofluorescence staining of methanol-fixed HeLa cells using PLC-γ2 (Ab-1217).
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PLC-γ2 (Ab-1217).

PLC gamma2 (Ab 1217) Antibody

CATALOG NUMBER: 79-427

Clonality:
Polyclonal
Tested Applications:
IF, IHC
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
PLC-gamma2 (Ab-1217) antibody was raised against a peptide sequence around aa.1215~1219 (F-L-Y-D-T) derived from Human PLCγ2.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC
Application Note:
Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Specificity:
This antibody detects endogenous level of total PLC-γ2 protein.
Predicted Molecular Weight:
150 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
PLCG2
Additional Names:
FCAS3, APLAID, PLC-IV, PLC-gamma-2, Afh, Fbl3a, Fbxl3a, Ovtm, PLC-gamma2, Phospholipase C-gamma-2
Protein Accession Number:
NP_002652.2
Protein Gi Number:
117320537
Ncbi Gene Id Number:
5336
Background:
The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
Background Reference 1:
Singer, W. D. et al. (1997) Annu. Rev. Biochem. 66, 475-509. Smrcka, A. V. et al. (1991) Science 251, 804-807. Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225. Watanabe, D. et al. (2001) J. Biol. Chem. 276, 38595-38601.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-427

List Size:
0.1 mg

List Price:

$370.00

Datasheet
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