PLCD3 Antibody

CATALOG NUMBER: 57-887

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PLCD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PLCD3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
89 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PLCD3
Additional Names:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3, Phosphoinositide phospholipase C-delta-3, Phospholipase C-delta-3, PLC-delta-3, PLCD3, KIAA1964
Protein Accession Number:
Q8N3E9
Protein Gi Number:
158706388
Ncbi Gene Id Number:
113026
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the phospholipase C family,which catalyze the hydrolysis of phosphatidylinositol4,5-bisphosphate to generate the second messengers diacylglyceroland inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3mediate a variety of cellular responses to extracellular stimuli byinducing protein kinase C and increasing cytosolic Ca(2+)concentrations. This enzyme localizes to the plasma membrane andrequires calcium for activation. Its activity is inhibited byspermine, sphingosine, and several phospholipids. [provided byRefSeq].
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Background Reference 3:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 4:
Newton-Cheh, C., et al. Nat. Genet. 41(6):666-676(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-887

List Size:
400 ul

List Price:

$495.00

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