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Western blot analysis of PLEKHM2 in rat brain tissue lysate with PLEKHM2 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of PLEKHM2 in human liver tissue with FAM59A antibody at 5 μg/mL.
Immunofluorescence of PLEKHM2 in Human Brain cells with PLEKHM2 antibody at 20 μg/mL.
Western blot analysis of PLEKHM2 in rat brain tissue lysate with PLEKHM2 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Trial Size

PLEKHM2 Antibody

CATALOG NUMBER: 5485

Clonality:
Polyclonal
Tested Applications:
ELISA, IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
PLEKHM2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM2.
The immunogen is located within the last 50 amino acids of PLEKHM2.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IF, IHC-P, WB
Application Note:
PLEKHM2 antibody can be used for detection of PLEKHM2 by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Positive Control 1:
Cat. No. 1463 - Rat Brain Tissue Lysate
Positive Control 2:
Cat. No. 10-201 - Human Liver Tissue Slide
Purification:
PLEKHM2 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
PLEKHM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
PLEKHM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PLEKHM2
Additional Names:
PLEKHM2 Antibody: SKIP, KIAA0842, SKIP, Pleckstrin homology domain-containing family M member 2, Salmonella-induced filaments A and kinesin-interacting protein, PH domain-containing family M member 2
Protein Accession Number:
CAH72018
Protein Gi Number:
55666400
Ncbi Gene Id Number:
23207
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PLEKHM2 Antibody: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
Background Reference 1:
Liu X-L, Yuan J-Y, Zhang J-W, et al. Differential gene expression in human hematopoietic stem cells specified toward erythroid, megakaryotic, and granulocytic lineage. J. Leuk. Biol.2007; 82:986-1002.
Background Reference 2:
Diacovich L, Dumont A, Lafitte D, et al. Interaction between the SifA virulence factor and its host target SKIP is essential for Salmonella pathogenesis. J. Biol. Chem.2009; 284:33151-60.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5485

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

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