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Recombinant

Plozalizumab (CCR2/CD192) – Research Grade Biosimilar

CATALOG NUMBER: 10-734

Clonality:
Recombinant Monoclonal
Conjugate:
Unconjugated
Specifications
source-species:
CHO cells
source-species:
CHO cells
Immunogen:
Humanized / CCR2/CD192 [Homo sapiens]
Conjugate:
Unconjugated
Purification:
>95%
Clonality:
Recombinant Monoclonal
Isotype:
IgG1-kappa
Buffer:
PBS buffer pH7.5
Concentration:
batch dependent
Storage Conditions:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage.
Additional Names:
MLN-1202,anti-CCR2,hu1D9
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Plozalizumab has been investigated for the treatment of Atherosclerosis. Plozalizumab, a novel humanized monoclonal antibody, specifically targets CCR2 chemokine receptors found on the surface of certain white blood cells including macrophages and monocytes. Preclinical studies suggest that CCR2 plays an important role in the trafficking of monocytes and macrophages to sites of inflammation. The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

10-734

List Size:
0.1 mg

List Price:

$515.00

Datasheet
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