PLSCR4 Antibody

CATALOG NUMBER: 57-390

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PLSCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human PLSCR4.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PLSCR4
Additional Names:
Phospholipid scramblase 4, PL scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1, PLSCR4
Protein Accession Number:
Q9NRQ2
Protein Gi Number:
212276457
Ncbi Gene Id Number:
57088
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)
Background Reference 3:
Py, B., et al. PLoS ONE(3), E5006 (2009) :
Background Reference 4:
Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-390

List Size:
400 ul

List Price:

$495.00

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