PMS1 Antibody

CATALOG NUMBER: 58-143

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-722 amino acids from the C-terminal region of human PMS1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PMS1
Additional Names:
PMS1 protein homolog 1, DNA mismatch repair protein PMS1, PMS1, PMSL1
Protein Accession Number:
P54277
Protein Gi Number:
1709683
Ncbi Gene Id Number:
5378
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein belonging to the DNA mismatchrepair mutL/hexB family. This protein is thought to be involved inthe repair of DNA mismatches, and it can form heterodimers withMLH1, a known DNA mismatch repair protein. Mutations in this genecause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3)either alone or in combination with mutations in other genesinvolved in the HNPCC phenotype, which is also known as Lynchsyndrome.
Background Reference 1:
Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
Background Reference 2:
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 3:
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Background Reference 4:
Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-143

List Size:
400 ul

List Price:

$495.00

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