PNMA3 Antibody

CATALOG NUMBER: 59-504

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PNMA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-412 amino acids from the C-terminal region of human PNMA3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
52 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PNMA3
Additional Names:
Paraneoplastic antigen Ma3, PNMA3, MA3
Protein Accession Number:
Q9UL41
Protein Gi Number:
296452862
Ncbi Gene Id Number:
29944
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is a member of the paraneoplastic antigen MA(PNMA) gene family, whose protein products share homology withretroviral Gag proteins. They are highly expressed in the brain andalso in a range of tumors associated with serious neurologicalphenotypes. PMID:16407312 reports the presence of a functional -1ribosomal frameshift signal (consisting of a heptanucleotide shiftmotif followed 3' by a pseudoknot structure) in this gene, however,the frame-shifted product has not been characterized. [provided byRefSeq].
Background Reference 1:
Wills, N.M., et al. J. Biol. Chem. 281(11):7082-7088(2006)
Background Reference 2:
Schuller, M., et al. J. Neuroimmunol. 169 (1-2), 172-176 (2005) :
Background Reference 3:
Rosenfeld, M.R., et al. Ann. Neurol. 50(3):339-348(2001)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-504

List Size:
400 ul

List Price:

$495.00

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