Start Your Project

🛍️Explore our Promotions page to discover current deals, limited-time offers, and more!🌟

Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

PNPLA6 Antibody

CATALOG NUMBER: 58-373

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PNPLA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1000-1029 amino acids from the C-terminal region of human PNPLA6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
150 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PNPLA6
Additional Names:
Neuropathy target esterase, Patatin-like phospholipase domain-containing protein 6, PNPLA6, NTE
Protein Accession Number:
Q8IY17
Protein Gi Number:
150403921
Ncbi Gene Id Number:
10908
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
PNPLA6 is a phospholipase that deacetylatesintracellular phosphatidylcholine to produce glycerophosphocholine.It is thought to function in neurite outgrowth and processelongation during neuronal differentiation. The protein is anchoredto the cytoplasmic face of the endoplasmic reticulum in bothneurons and non-neuronal cells. Mutations in this gene result inautosomal recessive spastic paraplegia, and the protein is thetarget for neurodegeneration induced by organophosphorus compoundsand chemical warfare agents. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background Reference 1:
Hein, N.D., et al. Toxicol. Lett. 199(1):1-5(2010)
Background Reference 2:
Chen, J.X., et al. Pharmacol. Res. 62(3):259-264(2010)
Background Reference 3:
Greiner, A.J., et al. Biochim. Biophys. Acta 1798(8):1533-1539(2010)
Background Reference 4:
Hein, N.D., et al. Toxicol. Lett. 196(2):67-73(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-373

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

$35 Dry Ice Shipment fee may be required on some items.

Note: Online orders only accepted for shipment within the USA. Click here for the list of international distributors.

Customize your order

Bulk Pricing Available

Custom Formulations: azide free, endotoxin testing & endotoxin removal.

Pair your antibody with a Lysate, Peptide, Control, & /OR Secondary Antibody.

Contact our Customer Care Team for more information

Custom Antibody Services

Speak to one of our custom antibody specialists to discuss your next custom antibody project.

New & Featured Products

HIV-1 p24 Antibody [9D2F6] (HRP)
HIV-1 p24 Antibody [9D2F6] (HRP)

CATALOG NUMBER: PM-7369-HRP

HIV-1 p24 Antibody [9D2F6] (biotin)
HIV-1 p24 Antibody [9D2F6] (biotin)

CATALOG NUMBER: PM-7369-biotin

HIV-1 p24 Antibody [9D2F6]
HIV-1 p24 Antibody [9D2F6]

CATALOG NUMBER: PM-7369