PNPO Antibody

CATALOG NUMBER: 63-923

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PNPO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the C-terminal region of human PNPO.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
30 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PNPO
Additional Names:
Pyridoxine-5'-phosphate oxidase, Pyridoxamine-phosphate oxidase, PNPO
Protein Accession Number:
Q9NVS9
Protein Gi Number:
37082126
Ncbi Gene Id Number:
55163
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
Background Reference 1:
Musayev, F.N., et al. J. Biol. Chem. 284(45):30949-30956(2009)
Background Reference 2:
Khayat, M., et al. Mol. Genet. Metab. 94(4):431-434(2008)
Background Reference 3:
Song, H., et al. Schizophr. Res. 97 (1-3), 264-270 (2007) :
Background Reference 4:
Mills, P.B., et al. Hum. Mol. Genet. 14(8):1077-1086(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-923

List Size:
400 ul

List Price:

$495.00

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