POLD3 Antibody

CATALOG NUMBER: 58-435

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This POLD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-443 amino acids from the C-terminal region of human POLD3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
51 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
POLD3
Additional Names:
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039
Protein Accession Number:
Q15054
Protein Gi Number:
17375506
Ncbi Gene Id Number:
10714
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The DNA polymerase delta complex is involved in DNAreplication and repair, and it consists of the proliferating cellnuclear antigen (PCNA; MIM 176740), the multisubunit replicationfactor C (see MIM 102579), and the 4 subunit polymerase complex:POLD1 (MIM 174761), POLD2 (MIM 600815), POLD3, and POLD4 (MIM611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied byOMIM].
Background Reference 1:
Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
Background Reference 2:
Baranovskiy, A.G., et al. Cell Cycle 7(19):3026-3036(2008)
Background Reference 3:
Baranovskiy, A.G., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 9), 822-824 (2008) :
Background Reference 4:
Lemmens, L., et al. Biochem. Biophys. Res. Commun. 367(2):264-270(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-435

List Size:
400 ul

List Price:

$495.00

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