PON1 Antibody

CATALOG NUMBER: 55-339

Clonality:
Polyclonal
Tested Applications:
Flow, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PON1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human PON1.
Conjugate:
Unconjugated
Tested Applications:
Flow, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
40 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PON1
Additional Names:
Serum paraoxonase/arylesterase 1, PON 1, Aromatic esterase 1, A-esterase 1, K-45, Serum aryldialkylphosphatase 1, PON1, PON
Protein Accession Number:
P27169
Protein Gi Number:
308153572
Ncbi Gene Id Number:
5444
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The enzyme encoded by this gene is an arylesterase thatmainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is anorganophosphorus anticholinesterase compound that is produced invivo by oxidation of the insecticide parathion. Polymorphisms inthis gene are a risk factor in coronary artery disease. The gene isfound in a cluster of three related paraoxonase genes at 7q21.3.
Background Reference 1:
Ergun, M.A., et al. Biochem. Genet. (2010) In press :
Background Reference 2:
Cagirci, G., et al. J. Heart Valve Dis. 19(4):453-458(2010)
Background Reference 3:
Mendonca, M.I., et al. Rev Port Cardiol 29(4):571-580(2010)
Background Reference 4:
Hashemi, M., et al. Genet. Mol. Res. 9(3):1735-1741(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-339

List Size:
400 ul

List Price:

$495.00

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