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Western blot analysis in HepG2 cell line lysates (35ug/lane).
PON2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Western blot analysis in HepG2 cell line lysates (35ug/lane).

PON2 Antibody

CATALOG NUMBER: 56-756

Clonality:
Polyclonal
Tested Applications:
Flow, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human PON2.
Conjugate:
Unconjugated
Tested Applications:
Flow, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PON2
Additional Names:
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2
Protein Accession Number:
Q15165
Protein Gi Number:
325511384
Ncbi Gene Id Number:
5445
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the paraoxonase gene family,which includes three known members located adjacent to each otheron the long arm of chromosome 7. The encoded protein isubiquitously expressed in human tissues, membrane-bound, and mayact as a cellular antioxidant, protecting cells from oxidativestress. Hydrolytic activity against acylhomoserine lactones,important bacterial quorum-sensing mediators, suggests the encodedprotein may also play a role in defense responses to pathogenicbacteria. Mutations in this gene may be associated with vasculardisease and a number of quantitative phenotypes related todiabetes. Alternatively spliced transcript variants encodingdifferent isoforms have been described.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Altenhofer, S., et al. J. Biol. Chem. 285(32):24398-24403(2010)
Background Reference 3:
Ticozzi, N., et al. Ann. Neurol. 68(1):102-107(2010)
Background Reference 4:
Wang, Y., et al. Diabet. Med. 27(4):376-383(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-756

List Size:
400 ul

List Price:

$495.00

Datasheet
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