POP1 Recombinant Protein

CATALOG NUMBER: 90-303

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
Human POP1 (aa 2-89) is fused at the N-terminus to a GST tag.
Fusion Tag:
GST tag
Application Note:
This recombinant proteins is for research use only.
Purity:
>95% (SDS-PAGE)
physical-state:
Lyophilized
Buffer:
Contains PBS. Reconstitute with 100 μl sterile water.
Concentration:
0.1mg/ml after reconstitution.
Storage Conditions:
Stable for at least 6 months after receipt when stored at -20°C.
Ncbi Official Symbol:
PYDC1
Additional Names:
Pyrin Domain-containing Protein 1, PAAD-only Protein 1, Pyrin-only Protein 1, PYC1
Protein Accession Number:
Q8WXC3
Protein Gi Number:
74730989
Ncbi Gene Id Number:
260434
Background:
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family (NLRs), including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). Pyrin domain-containing protein 1 (POP1) interacts with the protein Asc (Pycard) and modulates the interaction of Asc to NLR proteins.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-303

List Size:
10 ug

List Price:

$328.00

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