PP1R14C Antibody

CATALOG NUMBER: 55-061

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
This PP1R14C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-155 amino acids from the C-terminal region of human PP1R14C.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight:
18 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PPP1R14C
Additional Names:
Protein phosphatase 1 regulatory subunit 14C, Kinase-enhanced PP1 inhibitor, PKC-potentiated PP1 inhibitory protein, Serologically defined breast cancer antigen NY-BR-81, PPP1R14C, KEPI
Protein Accession Number:
Q8TAE6
Protein Gi Number:
90110047
Ncbi Gene Id Number:
81706
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The degree of protein phosphorylation is regulated by abalance of protein kinase and phosphatase activities. Proteinphosphatase-1 (PP1; see MIM 176875) is a signal-transducingphosphatase that influences neuronal activity, protein synthesis,metabolism, muscle contraction, and cell division. PPP1R14C is aninhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied byOMIM].
Background Reference 1:
Daskalow, K., et al. Anticancer Res. 30(5):1573-1578(2010)
Background Reference 2:
Scholz, S.W., et al. Ann. Neurol. 65(5):610-614(2009)
Background Reference 3:
Burgner, D., et al. PLoS Genet.(1), E1000319 (2009) :
Background Reference 4:
Mungall, A.J., et al. Nature 425(6960):805-811(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-061

List Size:
400 ul

List Price:

$495.00

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