PPP1R16B Antibody

CATALOG NUMBER: 59-308

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This PPP1R16B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-399 amino acids from the Central region of human PPP1R16B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
64 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PPP1R16B
Additional Names:
Protein phosphatase 1 regulatory inhibitor subunit 16B, Ankyrin repeat domain-containing protein 4, CAAX box protein TIMAP, TGF-beta-inhibited membrane-associated protein, hTIMAP, PPP1R16B, ANKRD4, KIAA0823
Protein Accession Number:
Q96T49
Protein Gi Number:
22256977
Ncbi Gene Id Number:
26051
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is membrane-associatedand contains five ankyrin repeats, a proteinphosphatase-1-interacting domain, and a carboxy-terminal CAAX boxdomain. Synthesis of the encoded protein is inhibited bytransforming growth factor beta-1. The protein may bind to themembrane through its CAAX box domain and may act as a signalingmolecule through interaction with protein phosphatase-1.Alternatively spliced transcript variants encoding differentisoforms have been identified in this gene.
Background Reference 1:
Csortos, C., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 295 (3), L440-L450 (2008) :
Background Reference 2:
Kim, K., et al. Biochem. Biophys. Res. Commun. 338(3):1327-1334(2005)
Background Reference 3:
Homma, K., et al. J. Mol. Biol. 343(5):1207-1220(2004)
Background Reference 4:
Cao, W., et al. Am. J. Physiol., Cell Physiol. 283 (1), C327-C337 (2002) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-308

List Size:
400 ul

List Price:

$495.00

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