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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

PPP2R1A Antibody

CATALOG NUMBER: 60-680

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig
Immunogen:
This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PPP2R1A
Additional Names:
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Medium tumor antigen-associated 61 kDa protein, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, PPP2R1A
Protein Accession Number:
P30153
Protein Gi Number:
143811355
Ncbi Gene Id Number:
5518
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a constant regulatory subunit of proteinphosphatase 2. Protein phosphatase 2 is one of the four majorSer/Thr phosphatases, and it is implicated in the negative controlof cell growth and division. It consists of a common heteromericcore enzyme, which is composed of a catalytic subunit and aconstant regulatory subunit, that associates with a variety ofregulatory subunits. The constant regulatory subunit A serves as ascaffolding molecule to coordinate the assembly of the catalyticsubunit and a variable regulatory B subunit. This gene encodes analpha isoform of the constant regulatory subunit A. Alternativelyspliced transcript variants have been described. [provided byRefSeq].
Background Reference 1:
Jones, S., et al. Science 330(6001):228-231(2010)
Background Reference 2:
Schmitz, M.H., et al. Nat. Cell Biol. 12(9):886-893(2010)
Background Reference 3:
Heikkinen, P.T., et al. J. Biol. Chem. 285(6):3740-3749(2010)
Background Reference 4:
Dupont, W.D., et al. Cancer 116(1):8-19(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-680

List Size:
400 ul

List Price:

$495.00

Datasheet
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