PPP2R5A Antibody

CATALOG NUMBER: 58-139

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This PPP2R5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-446 amino acids from the C-terminal region of human PPP2R5A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PPP2R5A
Additional Names:
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha, PPP2R5A
Protein Accession Number:
Q15172
Protein Gi Number:
7387496
Ncbi Gene Id Number:
5525
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The product of this gene belongs to the phosphatase 2Aregulatory subunit B family. Protein phosphatase 2A is one of thefour major Ser/Thr phosphatases, and it is implicated in thenegative control of cell growth and division. It consists of acommon heteromeric core enzyme, which is composed of a catalyticsubunit and a constant regulatory subunit, that associates with avariety of regulatory subunits. The B regulatory subunit mightmodulate substrate selectivity and catalytic activity. This geneencodes an alpha isoform of the regulatory subunit B56 subfamily.
Background Reference 1:
Flegg, C.P., et al. J. Biol. Chem. 285(24):18144-18154(2010)
Background Reference 2:
Freeman, A.K., et al. Cell Cycle 9(4):736-747(2010)
Background Reference 3:
Reece, K.M., et al. Biochem. Biophys. Res. Commun. 386(4):582-587(2009)
Background Reference 4:
Li, H., et al. Mol. Cell. Biol. 29(3):919-928(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-139

List Size:
400 ul

List Price:

$495.00

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