PRDX2 Antibody

CATALOG NUMBER: XW-7715

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
60-190
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Peroxiredoxin-2 antibody can be used for the detection of Peroxiredoxin-2 by Western Blot.
Predicted Molecular Weight:
21.8 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
PRDX2 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PRDX2
Additional Names:
NKEFB, TDPX1, Peroxiredoxin-2, Natural killer cell-enhancing factor B, NKEF-B, PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, HEL-S-2a, Peroxiredoxin2, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, Thiol-specific antioxidant protein, NKEF
Protein Accession Number:
NP_005800.1
Protein Gi Number:
5902726
Ncbi Gene Id Number:
7001
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
FUNCTION: Enhances natural killer (NK) cells activity.

CATALYTIC ACTIVITY: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.

SUBUNIT: Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration.

SIMILARITY: Belongs to the ahpC/TSA family.

SUBCELLULAR LOCATION: Cytoplasm.

MISCELLANEOUS: The active site is the redox-active Cys-50 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-171-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7715

List Size:
0.05 mg

List Price:

$565.00

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