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Western Blot at 1:1000 dilution + T47D whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + T47D whole cell lysate Lysates/proteins at 20 ug per lane.

PREX1 Antibody

CATALOG NUMBER: 63-957

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-594 amino acids from the Central region of human PREX1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
186 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PREX1
Additional Names:
Phosphatidylinositol 3,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,5)-dependent Rac exchanger 1, PREX1, KIAA1415
Protein Accession Number:
Q8TCU6
Protein Gi Number:
148886999
Ncbi Gene Id Number:
57580
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Background Reference 1:
Carretero-Ortega, J., et al. Mol. Pharmacol. 77(3):435-442(2010)
Background Reference 2:
Ledezma-Sanchez, B.A., et al. Biochem. Biophys. Res. Commun. 391(4):1647-1652(2010)
Background Reference 3:
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
Background Reference 4:
Qin, J., et al. Oncogene 28(16):1853-1863(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-957

List Size:
400 ul

List Price:

$495.00

Datasheet
Shipping Info

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