PRKCQ Antibody

CATALOG NUMBER: XW-7463

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human, Mouse, Rat
Immunogen:
610-673
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
PRKCQ antibody can be used for the detection of PRKCQ by Western blot, may also work for IHC and ICC.
Predicted Molecular Weight:
81.9 kDa (calculated)
Purification:
Antigen affinity-purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
PRKCQ antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PRKCQ
Additional Names:
PRKCT, Protein kinase C theta type, nPKC-theta, PRKCT, PRKCQ
Protein Accession Number:
NP_006248.1
Protein Gi Number:
5453976
Ncbi Gene Id Number:
5588
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Protein kinase C, Θ. PKC Θ is a calcium-independent, novel isoform that is important in transducing signals in T lymphocytes. Interaction of a T lymphocyte with an antigen-presenting cell results in clustering of the T cell antigen receptor (TCR) and the recruitment of a large signaling complex to the site of cell-cell contact. PKC Θ is essential for TCR-mediated activation. PKC Θ plays a role in pathways that link the TCR signaling complex to the activation of NF-κB in mature T lymphocytes.
Background Reference 1:
Sun, Z., Arendt, C. W., Ellmeier, W., Schaeffer, E. M., Sunshine, M. J., Gandhi, L., Annes, J., Petrzilka, D., Kupfer, A., Schwartzberg, P. L., Littman, D. R. PKC-theta is required for TCR-induced NF-kappa-B activation in mature but not immature T lymphocytes. Nature 404: 402-407, 2000.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7463

List Size:
0.05 mg

List Price:

$585.00

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