PRSS7 Antibody

CATALOG NUMBER: 56-304

Clonality:
Polyclonal
Tested Applications:
Flow, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.
Conjugate:
Unconjugated
Tested Applications:
Flow, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Predicted Molecular Weight:
113 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
TMPRSS15
Additional Names:
Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15, Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, TMPRSS15, ENTK, PRSS7
Protein Accession Number:
P98073
Protein Gi Number:
317373442
Ncbi Gene Id Number:
5651
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes an enzyme that converts the pancreaticproenzyme trypsinogen to trypsin, which activates other proenzymesincluding chymotrypsinogen and procarboxypeptidases. The precursorprotein is cleaved into two chains that form a heterodimer linkedby a disulfide bond. This protein is a member of the trypsin familyof peptidases. Mutations in this gene cause enterokinasedeficiency, a malabsorption disorder characterized by diarrhea andfailure to thrive.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)
Background Reference 3:
Vilen, S.T., et al. Exp. Cell Res. 314(4):914-926(2008)
Background Reference 4:
Imamura, T., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (6), G1235-G1241 (2003) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-304

List Size:
400 ul

List Price:

$495.00

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