PSMC5 Antibody

CATALOG NUMBER: 28-816

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
C. elegans, Dog, Drosophila, Human, Mouse, Rat, Zebrafish
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
C. elegans, Dog, Drosophila, Human, Mouse, Rat, Zebrafish
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC5.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
PSMC5 antibody can be used for detection of PSMC5 by ELISA at 1:312500. PSMC5 antibody can be used for detection of PSMC5 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
46 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store PSMC5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
PSMC5
Additional Names:
PSMC5, S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Protein Accession Number:
NP_002796
Protein Gi Number:
24497435
Ncbi Gene Id Number:
5705
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Background Reference 1:
Inoue, T., et al., (2006) Biochem. Biophys. Res. Commun. 342 (3), 829-834.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-816

List Size:
100 ul

List Price:

$473.00

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