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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

PSMD5 Antibody

CATALOG NUMBER: 60-676

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This PSMD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human PSMD5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
56 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
PSMD5
Additional Names:
26S proteasome non-ATPase regulatory subunit 5, 26S protease subunit S5 basic, 26S proteasome subunit S5B, PSMD5, KIAA0072
Protein Accession Number:
Q16401
Protein Gi Number:
3122657
Ncbi Gene Id Number:
5711
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The 26S proteasome is a multicatalytic proteinase complexwith a highly ordered structure composed of 2 complexes, a 20S coreand a 19S regulator. The 20S core is composed of 4 rings of 28non-identical subunits; 2 rings are composed of 7 alpha subunitsand 2 rings are composed of 7 beta subunits. The 19S regulator iscomposed of a base, which contains 6 ATPase subunits and 2non-ATPase subunits, and a lid, which contains up to 10 non-ATPasesubunits. Proteasomes are distributed throughout eukaryotic cellsat a high concentration and cleave peptides in anATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome,is the processing of class I MHC peptides. This gene encodes anon-ATPase subunit of the 19S regulator base.
Background Reference 1:
Roelofs, J., et al. Nature 459(7248):861-865(2009)
Background Reference 2:
Kaneko, T., et al. Cell 137(5):914-925(2009)
Background Reference 3:
Listovsky, T., et al. EMBO J. 23(7):1619-1626(2004)
Background Reference 4:
Conticello, S.G., et al. Curr. Biol. 13(22):2009-2013(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-676

List Size:
400 ul

List Price:

$495.00

Datasheet
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